Polymer-based nanocomposite materials, and non-crystalline multinary semiconductors are of great interest both from the point of view of fundamental and applied science, due to the potential use in high-tech fields, the possibility of simple processing and modification of the structurel units or morphology by laser, plasma or radiation techniques. The major objective of the project was to generate new knowledge and technologies on multifunctional hybrid nanocomposites of different architecture from polymers and non-crystalline semiconductors for priority areas in optoelectronics, photonics and biomedicine. The proposed topics included elaboration and synthesis of advanced materials and preparation of multilayer planar structures, of diffraction elements by holographic methods or by electron beam iradiation, of planar- or fiber optic nanostructured advanced sensors for environment and biomedicine, as well as of photoluminescent elements with high efficiency. The project targeted coordinating compounds with rare earth ions, bionanocomposites, as well as nanonocomposites based on multifunctional non-crystalline semiconductors. For the characterization of the new materials and structures, optical spectroscopy methods were used (UV-VIS, IR, Raman, photoluminescence), as well as the technique of SEM and AFM microscopy, etc. The photo- and electron-induced phenomena, as well as the phenomena of electric charge transport were studied. The project included development of theoretical models, analysis and interpretation of the obtained experimental data. Attention was paid to the study and theoretical modeling of the influence of the external fields on optical and kinetic characteristics of the various nanostructures, and nanocomposites. Nanoclusters of the "core-shell" type were studied, with applications in biomedicine, including biomarkers, as well as multifunctional hybrid materials for cell engineering. The biocomposites, to which cytochrome c and cardiolipin complexes are attributed, were modeled taking into account the experimental data of the kinetics of the reaction of the lipid peroxidation process. Based on the nanocomposite materials and obtained nanostructures the project aimed to develop advanced devices for optoelectronics, photonics and biomedicine: diffractional structures, thin-film or nanostructured fiber-optic advanced sensors (for example based on SERS effect, plasmonic resonance, etc.), high efficiency photoluminescence based elements.